Patterns of loss of heterozygosity in breast carcinoma during neoadjuvant chemotherapy
نویسندگان
چکیده
منابع مشابه
Patterns of loss of heterozygosity in breast carcinoma during neoadjuvant chemotherapy.
There is evidence indicating that resistance to some chemotherapy drugs is related to enhanced repair of DNA lesions. Microsatellite instability (MSI) and loss of heterozy-gosity (LOH) reflect genetic instability and are associated with specific DNA repair pathways. Despite the strong implication of genetic instability in breast cancer its association with chemotherapy is unknown. Thus, we anal...
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ژورنال
عنوان ژورنال: International Journal of Oncology
سال: 2007
ISSN: 1019-6439,1791-2423
DOI: 10.3892/ijo.30.5.1145